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Degree
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Ph. D. (Eng.), Associate Professor, Cybernetics Department, National Research Nuclear University MEPhI
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E-mail
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bioinf@rambler.ru
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Location
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Moscow
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Articles
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It is known that during evolution process new genes may be constructed by a combination of existing genes. The combination mainly based on two processes: fusionиof genes or parts of genes and insertion of one gene or part of gene into another. Triplet periodicity of coding sequences is a common property of most living organisms. The fusion and insertion events may give triplet periodicity change points in a corresponding position of the gene. For the change point analysis measures of difference and similarity of triplet periodicity were introduced. Based on these measures the mathematical method for paired and single change point search in genes was developed.
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